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KMID : 0380020190340040221
Korean Journal of Biotechnology and Bioengineering
2019 Volume.34 No. 4 p.221 ~ p.232
Chitosan-Vitamin C Nanoparticles
Deshmukh Aarti R.

Kim Beom-Soo
Abstract
Vitamin C is a very important module related to many biochemical functions of human body. Vitamin C is highly sensitive and can be lost if exposed to high temperature, humid air, light, and alkaline pH. In recent decades, use of chitosan nanoparticles as nanocarriers has received much attention due to their biocompatibility, biodegradability, and non-toxicity. Chitosan nanoparticles containing vitamins, flavors, enzymes, and antimicrobial agents can maintain their activity. Chitosan nanoparticles can stimulate the stabilization of vitamin C and improve controlled release. This review provides a summary of the preparation and characterization of chitosan nanoparticles and potential benefits of vitamin C-containing chitosan nanoparticles. In addition, biological functions, dietary restrictions, and mechanisms of vitamin C are reviewed. Various challenges and future scope for improving the properties of vitamin C using chitosan nanoparticles are also discussed.
KEYWORD
chitosan, vitamin C, anoparticles, ionic gelation
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